- A Case of Advanced Hepatocellular Carcinoma : Curative Resection after Repeated Transcatheter Arterial Chemoembolization, Systemic Chemotherapy and Radiotherapy
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So Yeon Lee, Seung Kew Yoon, Min Su Kim, Si Hyun Bae, Jong Young Choi, Byung Gil Choi, Ho Jong Chun, Dong Gu Kim, Seok Whan Moon
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Journal of the Korean Liver Cancer Study Group. 2006;6(1):38-41. Published online June 30, 2006
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Abstract
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- A 46 year-old male patient was admitted to our hospital for evaluation of hepatic mass which was detected on
ultrasonography. He had a history of chronic hepatitis B carrier. Laboratory findings showed that HBsAg was
positive, and HBeAg was negative. AFP was 2,081.1 ng/mL. Abdomen CT showed a large well-defined low
density lesion involving entire right hepatic lobe which was compatable with advanced hepatocellular carcinoma
(stage III). Celiac and hepatic arteriogram reveled huge hypervascular mass at both lobe of the liver.
Transcatheter arterial chemoembolization (TACE), systemic chemotherapy, percutaneous ethanol injection therapy
(PEIT), and radiotherapy were combined as the treatment of huge hepatoma. After combined therapy, tumor
decreased in size. As a result, curative right lobectomy could be performed. Six months after surgery, chest CT
showed two small metastatic nodules in both lung, so wedge resection was performed. We followed the patient
for 5 years after operation and there was no evidence of regional tumor recurrence or distant metastasis.
- A Case of Advanced Hepatocellular Carcinoma Treated with Hepatic Arterial Infusion Chemotherapy
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So Yeon Lee, Si Hyun Bae, Min Su Kim, Jong Young Choi, Seung Kew Yoon, Dong Hoon Lee, Ho Jong Choen
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Journal of the Korean Liver Cancer Study Group. 2006;6(1):52-55. Published online June 30, 2006
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Abstract
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- A 57 year-old-male patient was admitted to our hospital for evaluation of hepatic mass which was detected on
ultrasonography. He had history of chronic hepatitis B and alcoholism. Laboratory findings showed that HBsAg
was positive, and HBeAg was negative. AFP was 5.39 ng/mL. Abdominal CT showed large ill-defined low
density lesion in 4, 7 and 8 segment of the liver with tumor thrombosis at umbilical portion of left portal vein,
which was compatible with advanced hepatocellular carcinoma (stage IVb). Celiac and hepatic arteriogram
revealed huge hypervascular mass at both lobe of the liver. Chemoport catheter was inserted to the right hepatic
artery and intra-arterial chemotherapy (epirubicin 50 mg every 4 weeks, cisplatin 25 mg and 5-FU 200 mg
weekly) was started with continuous infusion device. After 3 cycles of repeated intra-arterial chemotherapy, tumor
mass in both hepatic lobe were decreased in size and extent. He is planned to be treated with additional
intra-arterial chemotherapy.
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